video phone beyonce mp3 How NHS Digital data is helping Oxford University research treatment for cardiovascular disease

An innovative use of NHS Digital data is helping the Nuffield Department of Public Health at the University of Oxford to provide clinical trial evidence for a potentially lifesaving new treatment for cardiovascular disease.

It is the first major international research study to use hospital admissions data directly from NHS Digital to identify potential participants.

That means the ORION-4 study is much more efficient – and it paves the way for other studies to use the same streamlined process.

ORION-4 is testing whether inclisiran – which, while not yet approved for use in any market, has already been shown in phase 2 trials to significantly reduce ‘bad’ cholesterol in the blood – cuts the chances of patients having heart attacks and stroke. The study will recruit 15,000 people who have previously had cardiovascular events, including 12,000 from the UK – which means inviting at
least half a million people.

In the past, researchers would ask up to 100 hospital trusts to identify suitable patients from their records. But this was very time-consuming for trusts and for the study team receiving
the data.

Not only does this accelerate research, it saves valuable NHS resources and significantly cuts the cost of clinical trials.

This study fits in with a national drive to find ways to better use data to improve the speed, efficiency and quality of clinical trials.

video phone beyonce mp3 How NHS Digital data is helping Oxford University research treatment for cardiovascular disease
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Science & Technology	Upload TimePublished on 12 Jul 2019

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